[Simnibs-discuss] Relative influence of cortical surface-based parameters on resulting efield model

[Axel Thielscher]

Hi Dan,


indeed, the local cortical features which you mentioned will influence 
the electric field. This is implicitly accountd for when you calculate 
the field based on individual head models that have anatomically 
accurate representations of the cortex. So, for calculating the field, 
there is no need to explicitly extract these features.


However, it is a different story when you try to understand which 
features explain how much of the electric field variability between 
subjects. Then, you will have to extract them (using some other program) 
to do a correlation analysis between the features and the field in some 
region of interest.


Best regards,

Axel



On 11/23/2020 10:18 PM, Mccalley, Daniel wrote:
> Hi all,
>
> I was wondering how/if different features of the cortical surface are 
> modeled in SIMNIBS.
>
> While I'm sure coil-to-cortex distance accounts for a substantial 
> portion of variance between individual electric field size/strength, I 
> would imagine that local features of the cortex such as cortical 
> thickness, orientation/complexity of gyri and/or sulcal depth are 
> incorporated into the modeling. Are these features somehow weighted or 
> accounted for when modeling electric fields?
>
> If so, what is the relative weighting or contribution of these factors 
> in determining the efield model? or alternatively, is it known what 
> portion of individual variance these features explain?
>
> Best,
>
> Dan McCalley
> Medical University of South Carolina
> College of Graduate Studies, Neuroscience
>
>
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-- 
Dr. Axel Thielscher
Associate Professor
Danish Research Center for Magnetic Resonance
Copenhagen University Hospital Hvidovre
DK-2650 Hvidovre, Denmark
www.drcmr.dk
&
Department of Health Technology
Technical University of Denmark
DK-2800 Kgs. Lyngby
http://www.healthtech.dtu.dk/

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