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<p>Hi Dan,</p>
<p><br>
</p>
<p>indeed, the local cortical features which you mentioned will
influence the electric field. This is implicitly accountd for when
you calculate the field based on individual head models that have
anatomically accurate representations of the cortex. So, for
calculating the field, there is no need to explicitly extract
these features.</p>
<p><br>
</p>
<p>However, it is a different story when you try to understand which
features explain how much of the electric field variability
between subjects. Then, you will have to extract them (using some
other program) to do a correlation analysis between the features
and the field in some region of interest.</p>
<p><br>
</p>
<p>Best regards,</p>
<p>Axel<br>
</p>
<p><br>
</p>
<p><br>
</p>
<div class="moz-cite-prefix">On 11/23/2020 10:18 PM, Mccalley,
Daniel wrote:<br>
</div>
<blockquote type="cite"
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Hi all,</div>
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<br>
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<div style="font-family: Calibri, Arial, Helvetica, sans-serif;
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I was wondering how/if different features of the cortical
surface are modeled in SIMNIBS.</div>
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<br>
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While I'm sure coil-to-cortex distance accounts for a
substantial portion of variance between individual electric
field size/strength, I would imagine that local features of the
cortex such as cortical thickness, orientation/complexity of
gyri and/or sulcal depth are incorporated into the modeling. Are
these features somehow weighted or accounted for when modeling
electric fields? </div>
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<br>
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If so, what is the relative weighting or contribution of these
factors in determining the efield model? or alternatively, is it
known what portion of individual variance these features
explain? </div>
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<br>
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Best, </div>
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<br>
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<div>
<div id="Signature">
<div>
<div style="font-family:Tahoma; font-size:13px">Dan McCalley
<div>Medical University of South Carolina</div>
<div>College of Graduate Studies, Neuroscience</div>
<div><br>
</div>
</div>
</div>
</div>
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<br>
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<pre class="moz-quote-pre" wrap="">_______________________________________________
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</pre>
</blockquote>
<pre class="moz-signature" cols="72">--
Dr. Axel Thielscher
Associate Professor
Danish Research Center for Magnetic Resonance
Copenhagen University Hospital Hvidovre
DK-2650 Hvidovre, Denmark
<a class="moz-txt-link-abbreviated" href="http://www.drcmr.dk">www.drcmr.dk</a>
&
Department of Health Technology
Technical University of Denmark
DK-2800 Kgs. Lyngby
<a class="moz-txt-link-freetext" href="http://www.healthtech.dtu.dk/">http://www.healthtech.dtu.dk/</a></pre>
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