[Simnibs-discuss] Targeting subject specific locations on the scalp

Mccalley, Daniel mccalled at musc.edu
Thu Jul 9 19:48:54 CEST 2020

Hi all,

Our lab targets the FP1 with TMS. We use a simple measurement system (http://clinicalresearcher.org/F3/) to locate exactly where we want to place the coil for each subject. Typically, we measure the subject's head, and then, starting from nasion, we'll move up Y mm and left X mm (where X and Y are determined from each subject's given head size).

Ideally, we'd like to create an electric field model for each subject that accounts for the TMS parameters as well as the exact location used. To implement this in SIMNIBS, I've tried the following:

1) Open a subjects m2m file and find the coordinates for nasion (say, for example, that these coordinates are X= -2.78, Y= 117.59, Z= -20.63).

2) Determine Y and X used to locate FP1 for the given subject (say, for example, that starting from nasion, we moved 37 mm in the Y direction, and over 32 mm in the X direction).

3) Subtract the displacements in the Y and X directions from the original nasion coordinates, resulting in X= -34.78 and Y=80.69

4) Add a new position wherein the reference coordinates match the original nasion coordinates (and the Define Reference Coordinates box is checked) and the coordinates calculated in step 3 are input in the position fields (Z is left blank for SIMNIBs to calculate)

5) Adjust for coil orientation and TMS parameters

This seems to have worked well for 90-95% of our subjects, however there are a few subjects in which the resulting coil placement appears to be over the eye (Note: Ordinarily I'd attach examples of the working and not-working subjects, but I'm not sure if the skin reconstruction of our participants falls under PHI).

Am I going about this the wrong way? Could this reflect a problem with segmentation/meshing? Or maybe a problem with the experimenter measurements of the subjects head? Any advice would be greatly appreciated. Thank you all so much!


Dan McCalley
Medical University of South Carolina
College of Graduate Studies, Neuroscience

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