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<p>Hi Witold,</p>
<p>CHARM was tested only on healthy appearing subjects without large
pathologies. I think the problem here is that as the subject brain
anatomy differs from the anatomical atlas substantially, the
algorithm starts modeling CSF as WM. This can be solved by
tweaking the parameters of CHARM, but in order to do that I would
need a few examples of the scans you're using if possible.</p>
<p>Best,<br>
Oula</p>
<p><br>
</p>
<div class="moz-cite-prefix">On 8/6/22 10:43, <a class="moz-txt-link-abbreviated" href="mailto:w.tomasz@sensusmed.pl">w.tomasz@sensusmed.pl</a>
wrote:<br>
</div>
<blockquote type="cite"
cite="mid:a2e3098e8f60e0a37124e8f4a142b693@sensusmed.pl">
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<div class="pre" style="margin: 0; padding: 0; font-family:
monospace"><span class="VIiyi"><span class="JLqJ4b ChMk0b"
data-language-for-alternatives="en"
data-language-to-translate-into="pl" data-phrase-index="0"
data-number-of-phrases="1"><span class="Q4iAWc">Hi everyone</span></span></span>,<br>
<br>
<span class="VIiyi"><span class="JLqJ4b ChMk0b"
data-language-for-alternatives="en"
data-language-to-translate-into="pl" data-phrase-index="0"
data-number-of-phrases="1"><span class="Q4iAWc">I wanted to
ask how the conduction issue will be resolved in people
after strokes and brain injuries.(optimization multifocal
of tDCS/tACS stimulation)</span></span></span><br>
<span class="VIiyi"><span class="JLqJ4b ChMk0b"
data-language-for-alternatives="en"
data-language-to-translate-into="pl" data-phrase-index="0"
data-number-of-phrases="2"><span class="Q4iAWc">In headreco,
the lesions were filled with cerebrospinal fluid, in CHARM
it is a clump of mainly white matter and gray sections.</span></span>
<span class="JLqJ4b ChMk0b"
data-language-for-alternatives="en"
data-language-to-translate-into="pl" data-phrase-index="1"
data-number-of-phrases="2"><span class="Q4iAWc">As we know,
quite a big difference.</span></span></span><br>
<span class="VIiyi"><span class="JLqJ4b ChMk0b"
data-language-for-alternatives="en"
data-language-to-translate-into="pl" data-phrase-index="0"
data-number-of-phrases="2"><span class="Q4iAWc">On the same
source file, we have big differences, Headreco is much
better at dealing with dilated cerebral ventricles etc.</span></span>
</span>CHARM fills them with gray matter, in addition, the
boundaries of gray matter and white matter are very divergent
over the entire surface.<br>
Such problems will not arise in other models in healthy people,
made with the same sequences on the same MR as in a stroke
survivor.<br>
Pictures in the attachment.<br>
I will appreciate your help and suggestions.<br>
<br>
Best,<br>
<div id="signature">-- <br>
<p><img src="cid:part1.m1oeYWk0.WeNPFRqV@drcmr.dk" class=""></p>
</div>
</div>
<br>
<fieldset class="moz-mime-attachment-header"></fieldset>
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