<html>
  <head>
    <meta http-equiv="Content-Type" content="text/html; charset=UTF-8">
  </head>
  <body>
    <p>Dear Athena,</p>
    <p>this is a good question which is not easy to answer. I would
      assume that the conductivity changes in gray and white matter
      correlate roughly with the diffusion changes seen in DTI. So a
      first step could be to simply quantify the diffusion changes
      compared to healthy subjects to get an initial impression on
      whether adjustments of the conductivity values might be needed.</p>
    <p>You can map the results back to subject-specific nifti or to MNI
      (using eg. the options menu in the GUI) to read out voxel-specfic
      values.<br>
    </p>
    <p>Best regards,</p>
    <p>Axel</p>
    <p><br>
    </p>
    <div class="moz-cite-prefix">On 3/23/2022 7:51 AM, Athena Stein
      wrote:<br>
    </div>
    <blockquote type="cite"
cite="mid:SYYP282MB13925B40E94A6A6F1CBE0388B4189@SYYP282MB1392.AUSP282.PROD.OUTLOOK.COM">
      <meta http-equiv="Content-Type" content="text/html; charset=UTF-8">
      <meta name="Generator" content="Microsoft Word 15 (filtered
        medium)">
      <!--[if !mso]><style>v\:* {behavior:url(#default#VML);}
o\:* {behavior:url(#default#VML);}
w\:* {behavior:url(#default#VML);}
.shape {behavior:url(#default#VML);}
</style><![endif]-->
      <style>@font-face
        {font-family:"Cambria Math";
        panose-1:2 4 5 3 5 4 6 3 2 4;}@font-face
        {font-family:Calibri;
        panose-1:2 15 5 2 2 2 4 3 2 4;}p.MsoNormal, li.MsoNormal, div.MsoNormal
        {margin:0cm;
        font-size:11.0pt;
        font-family:"Calibri",sans-serif;
        mso-fareast-language:EN-US;}span.EmailStyle17
        {mso-style-type:personal-compose;
        font-family:"Calibri",sans-serif;
        color:windowtext;}.MsoChpDefault
        {mso-style-type:export-only;
        font-family:"Calibri",sans-serif;
        mso-fareast-language:EN-US;}div.WordSection1
        {page:WordSection1;}</style><!--[if gte mso 9]><xml>
<o:shapedefaults v:ext="edit" spidmax="1026" />
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext="edit">
<o:idmap v:ext="edit" data="1" />
</o:shapelayout></xml><![endif]-->
      <div class="WordSection1">
        <p class="MsoNormal">Hi, <o:p></o:p></p>
        <p class="MsoNormal"><o:p> </o:p></p>
        <p class="MsoNormal">I was wondering how accurate simNIBS is
          when used in a brain with injury (especially diffuse axonal
          injury, gliosis etc.). e.g. is simNIBS able to do any kind of
          voxel-wise analysis which might capture these diffuse
          injuries? <o:p></o:p></p>
        <p class="MsoNormal"><o:p> </o:p></p>
        <p class="MsoNormal">I am hoping to use simNIBS to look into
          reverse calculation of tDCS needed in an attempt to
          standardise current dose at the cortex.<o:p></o:p></p>
        <p class="MsoNormal"><o:p> </o:p></p>
        <p class="MsoNormal">Thank you for all of your work – I am a big
          simNIBS fan!<o:p></o:p></p>
        <p class="MsoNormal"><o:p> </o:p></p>
        <p class="MsoNormal">Thanks<o:p></o:p></p>
        <p class="MsoNormal">Athena<o:p></o:p></p>
        <p class="MsoNormal"><o:p> </o:p></p>
        <p class="MsoNormal" style="background:white"><b><span
style="font-family:"Arial",sans-serif;color:#51247A;border:none
              windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU">Athena
              Stein</span></b><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal" style="background:white"><b><span
style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
              windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU">FHEA
              MPH BBiomedSc</span></b><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal" style="background:white"><span
style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU"> </span><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal" style="background:white"><span
style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU">PhD
            Candidate</span><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal" style="background:white"><span
style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU">Casual
            Academic</span><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal" style="background:white"><span
style="font-size:6.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU"> </span><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal" style="background:white"><span
style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU">UQ
            Child Health Research Centre</span><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal" style="background:white"><span
style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU">Acquired
            Brain Injury in Children research program (ABiC)</span><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal" style="background:white"><span
style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU">Centre
            for Children’s Health Research</span><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal" style="background:white"><span
style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU">Level
            6, 62 Graham St</span><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal" style="background:white"><span
style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU">South
            Brisbane Qld 4101 Australia</span><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal" style="background:white"><span
style="font-size:7.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU"> </span><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal" style="background:white"><b><span
style="font-size:7.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
              windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU">T</span></b><span
style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU"> +61
            7 3069 7555</span><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal" style="background:white"><b><span
style="font-size:7.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
              windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU">E</span></b><span
style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU"> </span><span
style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#201F1E;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU"><a
              href="mailto:a.stein@uq.edu.au" target="_blank"
              moz-do-not-send="true"><span style="color:#0563C1">a.stein@uq.edu.au</span></a></span><span
style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU"> </span><b><span
style="font-size:7.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
              windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU">W</span></b><span
style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU"> </span><span
style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#201F1E;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU"><a
              href="https://child-health-research.centre.uq.edu.au/"
              target="_blank" moz-do-not-send="true"><span
                style="color:#0563C1">child-health-research.centre.uq.edu.au</span></a></span><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal" style="background:white"><span
style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#2377CB;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU">               </span><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal" style="background:white"><span
style="font-size:7.5pt;font-family:"Arial",sans-serif;color:#51247A;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU">CRICOS
            00025B</span><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal" style="background:white"><span
style="font-size:6.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU"> </span><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal" style="background:white"><span
style="font-size:6.0pt;font-family:"Arial",sans-serif;color:#51247A;border:none
            windowtext 1.0pt;padding:0cm;mso-fareast-language:EN-AU"> </span><span
            style="color:#201F1E;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal"><span
            style="color:black;mso-fareast-language:EN-AU"><img
              style="width:6.25in;height:1.25in" id="Picture_x0020_1"
              src="cid:part1.NjSMq3A0.cgYeDtdy@drcmr.dk" class=""
              width="600" height="120" border="0"></span><span
            style="mso-fareast-language:EN-AU"><o:p></o:p></span></p>
        <p class="MsoNormal"><o:p> </o:p></p>
      </div>
      <br>
      <fieldset class="moz-mime-attachment-header"></fieldset>
      <pre class="moz-quote-pre" wrap="">_______________________________________________
Simnibs-discuss mailing list
<a class="moz-txt-link-abbreviated" href="mailto:Simnibs-discuss@drcmr.dk">Simnibs-discuss@drcmr.dk</a>
<a class="moz-txt-link-freetext" href="https://mailman.drcmr.dk/mailman/listinfo/simnibs-discuss">https://mailman.drcmr.dk/mailman/listinfo/simnibs-discuss</a>
</pre>
    </blockquote>
    <pre class="moz-signature" cols="72">-- 
Dr. Axel Thielscher
Professor of Neurophysics and Neuroimaging
Danish Research Center for Magnetic Resonance
Copenhagen University Hospital Hvidovre
DK-2650 Hvidovre, Denmark
<a class="moz-txt-link-abbreviated" href="http://www.drcmr.dk">www.drcmr.dk</a>
&
Department of Health Technology
Technical University of Denmark
DK-2800 Kgs. Lyngby
<a class="moz-txt-link-freetext" href="http://www.healthtech.dtu.dk/">http://www.healthtech.dtu.dk/</a></pre>
  </body>
</html>