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<p>Dear Athena,</p>
<p>this is a good question which is not easy to answer. I would
assume that the conductivity changes in gray and white matter
correlate roughly with the diffusion changes seen in DTI. So a
first step could be to simply quantify the diffusion changes
compared to healthy subjects to get an initial impression on
whether adjustments of the conductivity values might be needed.</p>
<p>You can map the results back to subject-specific nifti or to MNI
(using eg. the options menu in the GUI) to read out voxel-specfic
values.<br>
</p>
<p>Best regards,</p>
<p>Axel</p>
<p><br>
</p>
<div class="moz-cite-prefix">On 3/23/2022 7:51 AM, Athena Stein
wrote:<br>
</div>
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<p class="MsoNormal">Hi, <o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">I was wondering how accurate simNIBS is
when used in a brain with injury (especially diffuse axonal
injury, gliosis etc.). e.g. is simNIBS able to do any kind of
voxel-wise analysis which might capture these diffuse
injuries? <o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">I am hoping to use simNIBS to look into
reverse calculation of tDCS needed in an attempt to
standardise current dose at the cortex.<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Thank you for all of your work – I am a big
simNIBS fan!<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Thanks<o:p></o:p></p>
<p class="MsoNormal">Athena<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal" style="background:white"><b><span
style="font-family:"Arial",sans-serif;color:#51247A;border:none
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Stein</span></b><span
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<pre class="moz-quote-pre" wrap="">_______________________________________________
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<pre class="moz-signature" cols="72">--
Dr. Axel Thielscher
Professor of Neurophysics and Neuroimaging
Danish Research Center for Magnetic Resonance
Copenhagen University Hospital Hvidovre
DK-2650 Hvidovre, Denmark
<a class="moz-txt-link-abbreviated" href="http://www.drcmr.dk">www.drcmr.dk</a>
&
Department of Health Technology
Technical University of Denmark
DK-2800 Kgs. Lyngby
<a class="moz-txt-link-freetext" href="http://www.healthtech.dtu.dk/">http://www.healthtech.dtu.dk/</a></pre>
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