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<p>Hi,</p>
<p>the explanation by Pascual-Leone you give at the end of your
email is correct. However, the frequency of a single TMS pulse is
~ 3 to 7 kHz, which is high enough to induce currents that are
strong enough to depolarize the membranes.</p>
<p>The 1-25 Hz refer to the frequency at which TMS pulses are then
repeated to get neuromodulatory effects<br>
</p>
<p>Best,</p>
<p>Axel<br>
</p>
<div class="moz-cite-prefix">On 3/23/2021 1:25 AM, 刘习杰 wrote:<br>
</div>
<blockquote type="cite"
cite="mid:tencent_D1AF63A33A4FFA62B5011B93D901229BF809@qq.com">
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<div>Dear friends,</div>
<div><br>
</div>
<div>If you are familiar with it， please answer.</div>
<div><br>
</div>
<div>
<div>Recently, I am studying the comparison between Transcranial
Magnetic Stimulation (TMS) and tDCS. The essence of TMS is the
magnetic modulation, is it right? Or is the essence of TMS the
promotion of blood flow by a magnetic field? So, like the
magnetic field in MRI, the magnetic field force rotatations of
all electrons in the same direction?</div>
<div><br>
</div>
<div>Or does TMS work by inducting electric fields and currents?
But the frequency of TMS is only 1-25 Hz. </div>
<div><br>
</div>
<div>There's an explanation, saying TMS is delivered to the
brain by passing a strong brief electrical current through an
insulated wire coil placed on the skull. This rapid phasic
current flow generates a transient magnetic field, which
propagates in space and in turn induces a secondary current in
the brain that is capable of depolarising neurons if the coil
is held over the subject’s head (Pascual-Leone et al., 2002).</div>
</div>
<div><br>
</div>
<div>Thanks and Bests,</div>
<div><br>
</div>
<div>Jesse</div>
<br>
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<pre class="moz-signature" cols="72">--
Dr. Axel Thielscher
Associate Professor
Danish Research Center for Magnetic Resonance
Copenhagen University Hospital Hvidovre
DK-2650 Hvidovre, Denmark
<a class="moz-txt-link-abbreviated" href="http://www.drcmr.dk">www.drcmr.dk</a>
&
Department of Health Technology
Technical University of Denmark
DK-2800 Kgs. Lyngby
<a class="moz-txt-link-freetext" href="http://www.healthtech.dtu.dk/">http://www.healthtech.dtu.dk/</a></pre>
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