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<p>Hello,</p>
<p><br>
</p>
<p>In TMS, the time component and the spatial component of the
fields are decoupled. That means that we can write</p>
<p>E(x, t) = E(x)T(t)</p>
<p>E(x) is a component which is dependent on coil geometry, coil
position, and subject head geometry. That is what SimNIBS
calculates.</p>
<p>T(t) Depends only in pulse shape and stimulation intensity. It
does not affect the spatial distribution of the field, but rather
acts as a scaling parameter. For TMS, T(t) = dI(t)/dt, that is,
the rate of change of current through the coil. This means that
SimNIBS does not assume any particular time dynamics. Rather, it
takes a snapshot at the field at a single time point, typically at
the peak dI/dt value. For more time points, all you need to do is
to scale the field accordingly. <br>
</p>
<p>However, the peak dI/dt value is dependent on coil model,
stimulator model, pulse shape and pulse intensity. In some
stimulator models, this value is shown in the screen after a
pulse.<br>
</p>
<p>For more information, please see:
<a class="moz-txt-link-freetext" href="https://simnibs.github.io/simnibs/build/html/faq.html#what-is-the-di-dt-in-tms-simulations">https://simnibs.github.io/simnibs/build/html/faq.html#what-is-the-di-dt-in-tms-simulations</a><br>
</p>
<p><br>
</p>
<p>Best,</p>
<p>Guilherme</p>
<p><br>
</p>
<div class="moz-cite-prefix">On 13/03/2020 13.00, Mariacarla Memeo
wrote:<br>
</div>
<blockquote type="cite"
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<div class="WordSection1">
<p class="MsoNormal">To whom it may concerns, <o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">I’m Mariacarla Memeo and I work at the
Italian Institute of technology, in the Cognition Motion and
Neuroscience (<a
href="https://www.iit.it/research/lines/cognition-motion-and-neuroscience"
moz-do-not-send="true">CMON</a>) Unit. We usually use the
TMS with a single pulse protocol but recently we used a
continuous theta burst stimulation as in Huang et al., 2005
(DOI: 10.1016/j.neuron.2004.12.033): cTBS with three pulses at
50 Hz repeatedly applied at intervals of 200 ms (5 Hz) for 40
s.<o:p></o:p></p>
<p class="MsoNormal">I tried your software for a single pulse
protocol and I find it really useful but I was wondering if
there is a way to implement other TMS protocols, like the one
I reported.
<o:p></o:p></p>
<p class="MsoNormal">Thank you for your time.<o:p></o:p></p>
<p class="MsoNormal"><o:p></o:p></p>
<p class="MsoNormal">Best,<o:p></o:p></p>
<p class="MsoNormal" style="background:white"><span
style="font-size:10.0pt;color:black" lang="IT">********************************************************<o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><b><span
style="font-size:10.0pt;color:black" lang="IT">Mariacarla
Memeo</span></b><span style="font-size:10.0pt;color:black"
lang="IT">, PhD<o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span
style="font-size:10.0pt;color:black" lang="IT">C’MON Unit -
Fondazione Istituto Italiano di Tecnologia<o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span
style="font-size:10.0pt;color:black" lang="IT"> <o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span
style="font-size:10.0pt;color:black">Center for Human
Technologies<o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span
style="font-size:10.0pt;color:black">Via Enrico Melen 83,
16152 , building B, 7° floor<o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span
style="font-size:10.0pt;color:black"> <o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span
style="font-size:10.0pt;color:black">Phone: +39 010 8172239<o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span
style="font-size:10.0pt;color:black">IIT webpage: </span><span
style="font-size:10.0pt;color:black" lang="IT"><a
href="https://www.iit.it/people/mariacarla-memeo"
moz-do-not-send="true"><span style="color:#0563C1"
lang="EN-US">https://www.iit.it/people/mariacarla-memeo</span></a></span><span
style="font-size:10.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span
style="font-size:10.0pt;color:black">RG webpage: </span><span
style="font-size:10.0pt;color:black" lang="IT"><a
href="https://www.researchgate.net/profile/Mariacarla_Memeo"
moz-do-not-send="true"><span style="color:#0563C1"
lang="EN-US">https://www.researchgate.net/profile/Mariacarla_Memeo</span></a></span><span
style="font-size:10.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span
style="font-size:10.0pt;color:black" lang="IT">********************************************************</span><span
style="font-size:10.0pt;color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
</div>
<br>
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