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      <br>
      -------- Forwarded Message --------
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            <th valign="BASELINE" nowrap="nowrap" align="RIGHT">Subject:
            </th>
            <td>Re: ROI analysis</td>
          </tr>
          <tr>
            <th valign="BASELINE" nowrap="nowrap" align="RIGHT">Date: </th>
            <td>Tue, 17 Dec 2019 09:59:36 +0100</td>
          </tr>
          <tr>
            <th valign="BASELINE" nowrap="nowrap" align="RIGHT">From: </th>
            <td>Guilherme B Saturnino <a class="moz-txt-link-rfc2396E" href="mailto:guilhermebs@drcmr.dk"><guilhermebs@drcmr.dk></a></td>
          </tr>
          <tr>
            <th valign="BASELINE" nowrap="nowrap" align="RIGHT">To: </th>
            <td>Tulika Nandi <a class="moz-txt-link-rfc2396E" href="mailto:tulika.nandi@ndcn.ox.ac.uk"><tulika.nandi@ndcn.ox.ac.uk></a></td>
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      <p>Thank you!</p>
      <p>One more thing: If you opt for transforming simulation to nifti
        images, you also need to be carefull only to consider gray
        matter voxels in the analysis. For that, you can use the file or
        the masks in the m2m_subID/SUBID_final_contr.nii.gz or generate
        tissue masks with the "msh2nii" command (try "msh2nii --help") </p>
      <p><br>
      </p>
      <p>Best Regards,</p>
      <p>Guilherme<br>
      </p>
      <div class="moz-cite-prefix">On 17/12/2019 09.51, Tulika Nandi
        wrote:<br>
      </div>
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        cite="mid:3DA9F779-3C47-4884-8F48-BD2D67B1F752@ndcn.ox.ac.uk">
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          <p class="MsoNormal"><span style="font-size:11.0pt">Hi
              Guilherme,<o:p></o:p></span></p>
          <p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
          <p class="MsoNormal"><span style="font-size:11.0pt">Thank you
              for the guidance – I’ll try it out over the next few days.<o:p></o:p></span></p>
          <p class="MsoNormal"><span style="font-size:11.0pt">Yes,
              please feel free to share this. <o:p></o:p></span></p>
          <p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
          <div>
            <p class="MsoNormal"><span
                style="font-size:11.0pt;mso-fareast-language:EN-GB">Kind
                regards,<o:p></o:p></span></p>
            <p class="MsoNormal"><span
                style="font-size:11.0pt;mso-fareast-language:EN-GB"><o:p> </o:p></span></p>
            <p class="MsoNormal"><span
                style="font-size:11.0pt;mso-fareast-language:EN-GB">Tulika <o:p></o:p></span></p>
          </div>
          <p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
          <p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
          <div style="border:none;border-top:solid #B5C4DF
            1.0pt;padding:3.0pt 0cm 0cm 0cm">
            <p class="MsoNormal"><b><span style="color:black">From: </span></b><span
                style="color:black">Guilherme B Saturnino <a
                  class="moz-txt-link-rfc2396E"
                  href="mailto:guilhermebs@drcmr.dk"
                  moz-do-not-send="true"><guilhermebs@drcmr.dk></a><br>
                <b>Date: </b>Tuesday, 17 December 2019 at 08:42<br>
                <b>To: </b>Tulika Nandi <a
                  class="moz-txt-link-rfc2396E"
                  href="mailto:tulika.nandi@ndcn.ox.ac.uk"
                  moz-do-not-send="true"><tulika.nandi@ndcn.ox.ac.uk></a><br>
                <b>Subject: </b>Re: ROI analysis</span><span
                style="color:black;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
          </div>
          <div>
            <p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
          </div>
          <p>Dear Tulika,<o:p></o:p></p>
          <p>We are setting up a public mailing list for SimNIBS, and I
            think this conversation could be very useful for other
            people as well. Do you mind if I post it there?<o:p></o:p></p>
          <p><o:p> </o:p></p>
          <p>Best Regards,<o:p></o:p></p>
          <p>Guilherme<o:p></o:p></p>
          <p><o:p> </o:p></p>
          <div>
            <p class="MsoNormal">On 17/12/2019 09.41, Guilherme B
              Saturnino wrote:<o:p></o:p></p>
          </div>
          <blockquote style="margin-top:5.0pt;margin-bottom:5.0pt">
            <p>Dear Tulika,<o:p></o:p></p>
            <p>No problems, I'm happy to help.<o:p></o:p></p>
            <p><o:p> </o:p></p>
            <p>1- Depends. if it the head model was created with
              "headreco", the space is preserved so you can just use
              world coordinates from the original scan. However, if the
              model was created with "mri2mesh", changing to MNI space
              is probably a good idea as this pipeline changes the space
              of the images.<o:p></o:p></p>
            <p>2- Sure. Just use a L-infinity norm instead of an L-2
              norm.<br>
              roi <span class="pl-k">=</span> np.linalg.<span
                class="pl-token">norm</span>(elm_centers <span
                class="pl-k">-</span> ernie_coords, <span class="pl-v">axis</span><span
                class="pl-k">=</span><span class="pl-c1">1, <b>ord=np.inf</b></span>)
              <span class="pl-k"><</span> r<o:p></o:p></p>
            <p>Alternatively, you can transform simulation results to
              NifTi files and do the analysis there. There are several
              ways to do this in SimNIBS, such as setting
              Edit->Options->Interpolate to a nifti volume in the
              GUI, setting map_to_vol=True in scripts or running
              "msh2nii" on a ".msh" file.<o:p></o:p></p>
            <p><o:p> </o:p></p>
            <p>Best Regards,<o:p></o:p></p>
            <p>Guilherme<o:p></o:p></p>
            <div>
              <p class="MsoNormal">On 16/12/2019 17.43, Tulika Nandi
                wrote:<o:p></o:p></p>
            </div>
            <blockquote style="margin-top:5.0pt;margin-bottom:5.0pt">
              <p class="MsoNormal"><span style="font-size:11.0pt">Hi
                  Guilherme,</span><o:p></o:p></p>
              <p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
              <p class="MsoNormal"><span style="font-size:11.0pt">Sorry
                  to bother you again – I have one more question.</span><o:p></o:p></p>
              <p class="MsoNormal"><span style="font-size:11.0pt">We
                  have a voxel (in nifti format) in which MRS data was
                  obtained. We want to use this as an roi for estimating
                  the average current –</span><o:p></o:p></p>
              <ol style="margin-top:0cm" type="1" start="1">
                <li class="MsoListParagraph"
                  style="margin-left:0cm;mso-list:l0 level1 lfo3"><span
                    style="font-size:11.0pt">This voxel is already in
                    subject space. Is it necessary to move it to MNI
                    space and then get the center for doing the roi
                    analysis?</span><o:p></o:p></li>
                <li class="MsoListParagraph"
                  style="margin-left:0cm;mso-list:l0 level1 lfo3"><span
                    style="font-size:11.0pt">Can the roi be changed from
                    a sphere to a cube?</span><o:p></o:p></li>
              </ol>
              <p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
              <div>
                <p class="MsoNormal"><span
                    style="font-size:11.0pt;mso-fareast-language:EN-GB">Kind
                    regards,</span><o:p></o:p></p>
                <p class="MsoNormal"><span
                    style="font-size:11.0pt;mso-fareast-language:EN-GB"> </span><o:p></o:p></p>
                <p class="MsoNormal"><span
                    style="font-size:11.0pt;mso-fareast-language:EN-GB">Tulika </span><o:p></o:p></p>
              </div>
              <p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
              <p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
              <div style="border:none;border-top:solid #B5C4DF
                1.0pt;padding:3.0pt 0cm 0cm 0cm">
                <p class="MsoNormal"><b><span style="color:black">From:
                    </span></b><span style="color:black">Guilherme B
                    Saturnino <a href="mailto:guilhermebs@drcmr.dk"
                      moz-do-not-send="true"><guilhermebs@drcmr.dk></a><br>
                    <b>Date: </b>Tuesday, 3 December 2019 at 15:36<br>
                    <b>To: </b>Tulika Nandi <a
                      href="mailto:tulika.nandi@ndcn.ox.ac.uk"
                      moz-do-not-send="true"><tulika.nandi@ndcn.ox.ac.uk></a>,
                    Oula Puonti <a href="mailto:oupu@elektro.dtu.dk"
                      moz-do-not-send="true"><oupu@elektro.dtu.dk></a><br>
                    <b>Subject: </b>Re: ROI analysis</span><o:p></o:p></p>
              </div>
              <div>
                <p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
              </div>
              <p>Hi Tulika,<o:p></o:p></p>
              <p class="MsoNormal"
                style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"> <o:p></o:p></p>
              <p class="MsoNormal"
                style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><i>The
                  gmsh visualization popped up in a few seconds but
                  after that it took a while to run. I’ll try it again.</i><o:p></o:p></p>
              <p>It waits for the Gmsh window to be closed before
                continuing, so it might be just that?<o:p></o:p></p>
              <p class="MsoNormal"
                style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><i>I
                  would eventually like to run this on a cluster
                  (because the m2m folders are stored there), but save
                  the roi mesh and output (mean E field) to look at
                  later. Could you tell me how to do that?</i><o:p></o:p></p>
              <p>Sure, <o:p></o:p></p>
              <p>to save the roi mesh, just replace line 39 with<o:p></o:p></p>
              <p>gray_matter.write('gm_roi.msh')<o:p></o:p></p>
              <p>As to how to save the "mean_norm_E" in a file, I would
                probably append values to a python list and then write
                it out using for example<o:p></o:p></p>
              <p><a
href="https://docs.scipy.org/doc/numpy/reference/generated/numpy.savetxt.html#numpy.savetxt"
                  moz-do-not-send="true">numpy save</a><a
href="https://docs.scipy.org/doc/numpy/reference/generated/numpy.savetxt.html#numpy.savetxt"
                  moz-do-not-send="true">txt</a> (numpy is included with
                SimNIBS), or for more flexibility create a pandas
                DataFrame (you can install pandas with simnibs_python -m
                pip install pandas).<o:p></o:p></p>
              <p> <o:p></o:p></p>
              <p>Best,<o:p></o:p></p>
              <p>Guilherme<o:p></o:p></p>
              <p> <o:p></o:p></p>
              <div>
                <p class="MsoNormal">On 03/12/2019 16.11, Tulika Nandi
                  wrote:<o:p></o:p></p>
              </div>
              <blockquote style="margin-top:5.0pt;margin-bottom:5.0pt">
                <p class="MsoNormal"><span style="font-size:11.0pt">Hi
                    Guilherme,</span><o:p></o:p></p>
                <p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
                <p class="MsoNormal"><span style="font-size:11.0pt">The
                    gmsh visualization popped up in a few seconds but
                    after that it took a while to run. I’ll try it
                    again.</span><o:p></o:p></p>
                <p class="MsoNormal"><span style="font-size:11.0pt">I
                    would eventually like to run this on a cluster
                    (because the m2m folders are stored there), but save
                    the roi mesh and output (mean E field) to look at
                    later. Could you tell me how to do that?</span><o:p></o:p></p>
                <p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
                <div>
                  <p class="MsoNormal"><span
                      style="font-size:11.0pt;mso-fareast-language:EN-GB">Thanks!</span><o:p></o:p></p>
                  <p class="MsoNormal"><span
                      style="font-size:11.0pt;mso-fareast-language:EN-GB"> </span><o:p></o:p></p>
                  <p class="MsoNormal"><span
                      style="font-size:11.0pt;mso-fareast-language:EN-GB">Tulika </span><o:p></o:p></p>
                </div>
                <p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
                <p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
                <div style="border:none;border-top:solid #B5C4DF
                  1.0pt;padding:3.0pt 0cm 0cm 0cm">
                  <p class="MsoNormal"><b><span style="color:black">From:
                      </span></b><span style="color:black">Guilherme B
                      Saturnino <a href="mailto:guilhermebs@drcmr.dk"
                        moz-do-not-send="true"><guilhermebs@drcmr.dk></a><br>
                      <b>Date: </b>Tuesday, 3 December 2019 at 15:07<br>
                      <b>To: </b>Tulika Nandi <a
                        href="mailto:tulika.nandi@ndcn.ox.ac.uk"
                        moz-do-not-send="true"><tulika.nandi@ndcn.ox.ac.uk></a>,
                      Oula Puonti <a href="mailto:oupu@dtu.dk"
                        moz-do-not-send="true"><oupu@dtu.dk></a><br>
                      <b>Subject: </b>Re: ROI analysis</span><o:p></o:p></p>
                </div>
                <div>
                  <p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
                </div>
                <p>Hi Tulika,<o:p></o:p></p>
                <p> <o:p></o:p></p>
                <p>Thanks.<o:p></o:p></p>
                <p>The code looks fine, but it's weird it takes so long.
                  In every machine I've tried it runs in a few seconds.<o:p></o:p></p>
                <p>Maybe it gets stuck in the plotting (line 39)?<o:p></o:p></p>
                <p> <o:p></o:p></p>
                <p>Best Regards,<o:p></o:p></p>
                <p>Guilherme<o:p></o:p></p>
                <p> <o:p></o:p></p>
                <div>
                  <p class="MsoNormal">On 03/12/2019 15.52, Tulika Nandi
                    wrote:<o:p></o:p></p>
                </div>
                <blockquote style="margin-top:5.0pt;margin-bottom:5.0pt">
                  <p class="MsoNormal"><span style="font-size:11.0pt">Thanks
                      Oula!</span><o:p></o:p></p>
                  <p class="MsoNormal"><span style="font-size:11.0pt">Guilherme,
                      please see the attached script – it is essentially
                      the script that you provide with just the
                      filenames and paths changed. It took about a
                      couple hours to run – which is not a problem, I
                      just want to make sure I’m not doing something
                      wrong</span><o:p></o:p></p>
                  <p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
                  <div>
                    <p class="MsoNormal"><span
                        style="font-size:11.0pt;mso-fareast-language:EN-GB">Kind
                        regards,</span><o:p></o:p></p>
                    <p class="MsoNormal"><span
                        style="font-size:11.0pt;mso-fareast-language:EN-GB"> </span><o:p></o:p></p>
                    <p class="MsoNormal"><span
                        style="font-size:11.0pt;mso-fareast-language:EN-GB">Tulika </span><o:p></o:p></p>
                  </div>
                  <p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
                  <p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
                  <div style="border:none;border-top:solid #B5C4DF
                    1.0pt;padding:3.0pt 0cm 0cm 0cm">
                    <p class="MsoNormal"><b><span style="color:black">From:
                        </span></b><span style="color:black">Oula Puonti
                        <a href="mailto:oupu@dtu.dk"
                          moz-do-not-send="true"><oupu@dtu.dk></a><br>
                        <b>Date: </b>Tuesday, 3 December 2019 at 14:49<br>
                        <b>To: </b>Tulika Nandi <a
                          href="mailto:tulika.nandi@ndcn.ox.ac.uk"
                          moz-do-not-send="true"><tulika.nandi@ndcn.ox.ac.uk></a><br>
                        <b>Cc: </b>Guilherme B Saturnino <a
                          href="mailto:guilhermebs@drcmr.dk"
                          moz-do-not-send="true"><guilhermebs@drcmr.dk></a><br>
                        <b>Subject: </b>Re: ROI analysis</span><o:p></o:p></p>
                  </div>
                  <div>
                    <p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
                  </div>
                  <div id="divtagdefaultwrapper">
                    <p><span style="font-size:12.0pt;color:black">Hi
                        Tulika,</span><o:p></o:p></p>
                    <p><span style="font-size:12.0pt;color:black"> </span><o:p></o:p></p>
                    <p><span style="font-size:12.0pt;color:black">Was
                        this a e-field ROI analysis? Can you maybe send
                        me the script you used?</span><o:p></o:p></p>
                    <p><span style="font-size:12.0pt;color:black"> </span><o:p></o:p></p>
                    <p><span style="font-size:12.0pt;color:black">I'm
                        including Guilherme in this script as he's more
                        familiar with the e-field analysis part.</span><o:p></o:p></p>
                    <p><span style="font-size:12.0pt;color:black"> </span><o:p></o:p></p>
                    <p><span style="font-size:12.0pt;color:black">Best,</span><o:p></o:p></p>
                    <p><span style="font-size:12.0pt;color:black">Oula</span><o:p></o:p></p>
                    <p><span style="font-size:12.0pt;color:black"> </span><o:p></o:p></p>
                  </div>
                  <div class="MsoNormal" style="text-align:center"
                    align="center"><span
                      style="font-size:11.0pt;mso-fareast-language:EN-GB">
                      <hr width="100%" size="0" align="center"> </span></div>
                  <div id="divRplyFwdMsg">
                    <p class="MsoNormal"><b><span
                          style="font-size:11.0pt;color:black;mso-fareast-language:EN-GB">From:</span></b><span
style="font-size:11.0pt;color:black;mso-fareast-language:EN-GB"> Tulika
                        Nandi <a
                          href="mailto:tulika.nandi@ndcn.ox.ac.uk"
                          moz-do-not-send="true"><tulika.nandi@ndcn.ox.ac.uk></a><br>
                        <b>Sent:</b> Tuesday, December 3, 2019 3:44:29
                        PM<br>
                        <b>To:</b> Oula Puonti<br>
                        <b>Subject:</b> Re: ROI analysis</span><span
                        style="font-size:11.0pt;mso-fareast-language:EN-GB">
                      </span><o:p></o:p></p>
                    <div>
                      <p class="MsoNormal"><span
                          style="font-size:11.0pt;mso-fareast-language:EN-GB"> </span><o:p></o:p></p>
                    </div>
                  </div>
                  <div>
                    <p class="MsoNormal"><span style="font-size:11.0pt">I
                        was trying it for a single subject and it took
                        about a couple hours.</span><o:p></o:p></p>
                    <p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
                    <div>
                      <p class="MsoNormal"><span
                          style="font-size:11.0pt;mso-fareast-language:EN-GB">Kind
                          regards,</span><o:p></o:p></p>
                      <p class="MsoNormal"><span
                          style="font-size:11.0pt;mso-fareast-language:EN-GB"> </span><o:p></o:p></p>
                      <p class="MsoNormal"><span
                          style="font-size:11.0pt;mso-fareast-language:EN-GB">Tulika </span><o:p></o:p></p>
                    </div>
                    <p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
                    <p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
                    <div style="border:none;border-top:solid #B5C4DF
                      1.0pt;padding:3.0pt 0cm 0cm 0cm">
                      <p class="MsoNormal"><b><span style="color:black">From:
                          </span></b><span style="color:black">Oula
                          Puonti <a href="mailto:oupu@dtu.dk"
                            moz-do-not-send="true"><oupu@dtu.dk></a><br>
                          <b>Date: </b>Tuesday, 3 December 2019 at
                          14:43<br>
                          <b>To: </b>Tulika Nandi <a
                            href="mailto:tulika.nandi@ndcn.ox.ac.uk"
                            moz-do-not-send="true"><tulika.nandi@ndcn.ox.ac.uk></a><br>
                          <b>Subject: </b>Re: ROI analysis</span><o:p></o:p></p>
                    </div>
                    <div>
                      <p class="MsoNormal"><span
                          style="font-size:11.0pt"> </span><o:p></o:p></p>
                    </div>
                    <div id="divtagdefaultwrapper">
                      <p><span style="font-size:12.0pt;color:black">Hi
                          Tulika,</span><o:p></o:p></p>
                      <p><span style="font-size:12.0pt;color:black"> </span><o:p></o:p></p>
                      <p><span style="font-size:12.0pt;color:black">I
                          wouldn't expect that unless the mesh is huge.</span><o:p></o:p></p>
                      <p><span style="font-size:12.0pt;color:black"> </span><o:p></o:p></p>
                      <p><span style="font-size:12.0pt;color:black">Is
                          this a single subject only or over the a
                          group?</span><o:p></o:p></p>
                      <p><span style="font-size:12.0pt;color:black"> </span><o:p></o:p></p>
                      <p><span style="font-size:12.0pt;color:black">Best,</span><o:p></o:p></p>
                      <p><span style="font-size:12.0pt;color:black">Oula</span><o:p></o:p></p>
                      <p><span style="font-size:12.0pt;color:black"> </span><o:p></o:p></p>
                    </div>
                    <div class="MsoNormal" style="text-align:center"
                      align="center"><span
                        style="font-size:11.0pt;mso-fareast-language:EN-GB">
                        <hr width="100%" size="0" align="center"> </span></div>
                    <div id="divRplyFwdMsg">
                      <p class="MsoNormal"><b><span
                            style="font-size:11.0pt;color:black;mso-fareast-language:EN-GB">From:</span></b><span
style="font-size:11.0pt;color:black;mso-fareast-language:EN-GB"> Tulika
                          Nandi <a
                            href="mailto:tulika.nandi@ndcn.ox.ac.uk"
                            moz-do-not-send="true"><tulika.nandi@ndcn.ox.ac.uk></a><br>
                          <b>Sent:</b> Tuesday, December 3, 2019 3:41:02
                          PM<br>
                          <b>To:</b> Oula Puonti<br>
                          <b>Subject:</b> ROI analysis</span><span
                          style="font-size:11.0pt;mso-fareast-language:EN-GB">
                        </span><o:p></o:p></p>
                      <div>
                        <p class="MsoNormal"><span
                            style="font-size:11.0pt;mso-fareast-language:EN-GB"> </span><o:p></o:p></p>
                      </div>
                    </div>
                    <div>
                      <p class="MsoNormal"><span
                          style="font-size:11.0pt">Hi Oula,</span><o:p></o:p></p>
                      <p class="MsoNormal"><span
                          style="font-size:11.0pt"> </span><o:p></o:p></p>
                      <p class="MsoNormal"><span
                          style="font-size:11.0pt">Quick question about
                          the ROI analysis code – is it expected to take
                          more than 2 hrs to run?</span><o:p></o:p></p>
                      <p class="MsoNormal"><span
                          style="font-size:11.0pt"> </span><o:p></o:p></p>
                      <p class="MsoNormal"><span
                          style="font-size:11.0pt;mso-fareast-language:EN-GB">Kind
                          regards,</span><o:p></o:p></p>
                      <p class="MsoNormal"><span
                          style="font-size:11.0pt;mso-fareast-language:EN-GB"> </span><o:p></o:p></p>
                      <p class="MsoNormal"><span
                          style="font-size:11.0pt;mso-fareast-language:EN-GB">Tulika </span><o:p></o:p></p>
                      <p class="MsoNormal"> <o:p></o:p></p>
                    </div>
                  </div>
                </blockquote>
              </blockquote>
            </blockquote>
          </blockquote>
        </div>
      </blockquote>
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